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Golden Label Collection

The Golden Label Collection offers a comprehensive range of high-quality food supplements, designed to support your everyday wellness needs. This extensive collection features carefully formulated products that blend essential vitamins, minerals, and nutrients, making it ideal for those seeking effective, general health support. Trusted for its quality and versatility, the Golden Label Collection caters to a wide array of health goals.

Comprehensive Support

Golden Label products provide a full spectrum of essential nutrients, carefully balanced to support your daily health needs.

Quality Assurance

Each product undergoes rigorous testing to ensure purity, potency, and effectiveness.

Scientific Formulation

Formulas are developed based on the latest scientific research and nutritional understanding.

Versatile Solutions

From basic vitamins to specialized nutrient blends, the Golden Label collection meets diverse health needs.

AHCC

AHCC

Alpha-lipoic acid (ALA) was first isolated in 1951 by Lester Reed, a biochemist at the University of Texas. Reed was studying the enzymes involved in the metabolism of pyruvate, a molecule that plays a crucial role in energy production, at the cellular level, within mitochondria. He discovered that ALA was a cofactor for these enzymes involved in the Krebs cycle, meaning it was necessary for them to function properly. ALA is considered a “vitamine-like” substance due to its essential role in the body, even though it’s not technically a vitamin. It can be obtained through dietary sources like meat, spinach, and potatoes, or as a supplement. Since its discovery, ALA has been the subject of extensive research, and it is now known to have a wide range of biological activities. Over time, it was found that alpha-lipoic acid exists in two distinct forms: R-lipoic acid and S-lipoic acid, with R-lipoic acid being the naturally occurring and biologically active isomer in the human body. The Sodium Salt of R-Lipoic Acid represents an evolution in the delivery of this compound. While standard alpha-lipoic acid supplements contain both the R and S isomers, it was discovered that the R form is superior in terms of bioavailability and efficacy. However, pure R-lipoic acid, though more potent, is less stable and more difficult for the body to absorb when used in supplements. This led to the development of the Sodium Salt of R-Lipoic Acid—a stabilized version of the natural R-isomer, which significantly improves its stability, absorption, and bioavailability. Sodium Salt of R-Lipoic Acid is a highly regarded form of the naturally occurring antioxidant alpha-lipoic acid, a compound with a rich history and fascinating role in human metabolism. What makes the sodium salt form stand out is its ability to overcome the limitations of traditional R-lipoic acid. Pure R-lipoic acid is prone to rapid degradation when exposed to light, heat, and moisture, which can diminish its effectiveness. By binding R-lipoic acid to sodium, the resulting salt form ensures greater stability and quicker dissolution in the body, allowing for enhanced absorption and consistent delivery. Thus, Sodium Salt of R-Lipoic Acid offers a highly bioavailable and stable form, making it a superior option compared to regular R-lipoic acid and the racemic mixture of alpha-lipoic acid, which contains the less active S-isomer. This innovation in supplement formulation provides a more efficient way to harness the potential benefits of R-lipoic acid, making it a preferred choice for those seeking to maximize the effectiveness of their nutritional regimen.

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Advanced R Lipoic Acid

Advanced R Lipoic Acid

Alpha-lipoic acid (ALA) was first isolated in 1951 by Lester Reed, a biochemist at the University of Texas. Reed was studying the enzymes involved in the metabolism of pyruvate, a molecule that plays a crucial role in energy production, at the cellular level, within mitochondria. He discovered that ALA was a cofactor for these enzymes involved in the Krebs cycle, meaning it was necessary for them to function properly. ALA is considered a “vitamine-like” substance due to its essential role in the body, even though it’s not technically a vitamin. It can be obtained through dietary sources like meat, spinach, and potatoes, or as a supplement. Since its discovery, ALA has been the subject of extensive research, and it is now known to have a wide range of biological activities. Over time, it was found that alpha-lipoic acid exists in two distinct forms: R-lipoic acid and S-lipoic acid, with R-lipoic acid being the naturally occurring and biologically active isomer in the human body. The Sodium Salt of R-Lipoic Acid represents an evolution in the delivery of this compound. While standard alpha-lipoic acid supplements contain both the R and S isomers, it was discovered that the R form is superior in terms of bioavailability and efficacy. However, pure R-lipoic acid, though more potent, is less stable and more difficult for the body to absorb when used in supplements. This led to the development of the Sodium Salt of R-Lipoic Acid—a stabilized version of the natural R-isomer, which significantly improves its stability, absorption, and bioavailability. Sodium Salt of R-Lipoic Acid is a highly regarded form of the naturally occurring antioxidant alpha-lipoic acid, a compound with a rich history and fascinating role in human metabolism. What makes the sodium salt form stand out is its ability to overcome the limitations of traditional R-lipoic acid. Pure R-lipoic acid is prone to rapid degradation when exposed to light, heat, and moisture, which can diminish its effectiveness. By binding R-lipoic acid to sodium, the resulting salt form ensures greater stability and quicker dissolution in the body, allowing for enhanced absorption and consistent delivery. Thus, Sodium Salt of R-Lipoic Acid offers a highly bioavailable and stable form, making it a superior option compared to regular R-lipoic acid and the racemic mixture of alpha-lipoic acid, which contains the less active S-isomer. This innovation in supplement formulation provides a more efficient way to harness the potential benefits of R-lipoic acid, making it a preferred choice for those seeking to maximize the effectiveness of their nutritional regimen.

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Agaricus Extract Pure

Agaricus Extract Pure

Agaricus blazei Murrill, often referred to as ABM, is a type of mushroom native to Brazil and widely cultivated in Japan, where it is used both in the kitchen and medicinally. The Murrill species is named after mycologist William A. Murrill, who found and identified the mushroom growing on a friend’s lawn in Florida. This mushroom is sought after by health-conscious consumers for its unique properties and is commonly used in various forms, including dried mushrooms, capsules, powders, and teas. Agaricus blazei Murrill contains a rich profile of vitamins, minerals, amino acids and polysaccharides (beta-glucans), which have been the subject of scientific research. The most valuable part of Agaricus is the fully ripened fruiting body. MCS Formulas Agaricus extract is harvested, then gently dried to preserve its vitamins, polysaccharides, and trace elements. The shell broken process ensures the production of extremely fine powder that is 10x more powerful than ordinary Agaricus powders. This results in enhanced bioavailability.

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Ashwagandha

Ashwagandha

An Ayurvedic herb with a long history of use in traditional Indian medicine, ashwagandha belongs to the Solanaceae family—often referred to as nightshades—which includes tomatoes and potatoes. Known scientifically as Withania somnifera, it has been cultivated for thousands of years due to its potential health benefits. Ashwagandha is possibly an adaptogenic herb * [EFSA ID 3251]. (Adaptogens are natural substances, typically derived from plants or mushrooms, that are believed to contribute to optimal relaxation and emotional balance, and maintain overall balance and well-being.)* [EFSA ID 2183]. As such, ashwagandha is often used in herbal medicine and holistic health practices. Along with Astragalus membranaceous (available as MCS Formulas Astragaloside IV.) ashwagandha is one of the most prominent herbs in Ayurveda.

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Astragaloside

Astragaloside

Astragalus is a perennial herb predominantly found in East Asian regions. Belonging to the Fabaceae family, it has been cultivated for centuries. With its scientific name Astragalus membranaceus (also called Milkvetch and Huang Qi), this plant has captured the interest of researchers and consumers alike. Traditionally used in various medicinal practices, astragalus has a rich historical background. Its root is the part most commonly utilized. Characterized by its specific botanical properties, astragalus contains a complex array of compounds such as polysaccharide, flavonoids compounds, saponins compounds and alkaloids. These compounds contribute to the plant’s unique characteristics, making it a subject of ongoing scientific exploration. Of these, Astragaloside IV is an outstanding natural component in Astragalus membranaceus, connected with many of its important properties. On hold claims currently investigated for approval or rejection by EFSA in relation to Astragalus membranaceus are related to Immune health [EFSA ID 3735 and 3736], physical and mental well-being [EFSA ID 3255], heart [EFSA ID 3257], Joints [EFSA ID 3259 and 3260] and skin [EFSA ID 3261]*.

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Black Cumin Seed Oil

Black Cumin Seed Oil

Black Cumin Seed and its Oil (also called Nigella sativa) is a natural dietary supplement, that has been used by various civilization around the world for centuries. It has been used both as a spice and flavoring agent in variety of food preparations, as well as a traditional medicine to address various animal and human ailments. Due to its contribution to life, Black Cumin has a very rich history and it has been even called ”the seed of blessing”. Black cumin seeds have been found in the tomb of Egyptian Pharaoh Tutankhamen, as one of the several accompanying articles. Hippocrates and Dioscorides spoke about it as ‘Melanthion’, while the Bible describes it as the “curative black cumin” (Isaiah 28:25, 27 NKJV). Based on all its history and recent science, some argue that this is one of the most powerful medicinal plants known to man. Typically, black cumin oil contains 1.06 to 4.07 mg/g Thymoquinone and 32 to 40% fatty acids, such as linoleic acid (polyunsaturated omega 6 fatty acid). Next to this, black cumin oi also typically contains Phytosterols. The total sterols content of black cumin seed oil seems to be between 18 and 42%, while the major sterols identified were β-sitosterol, campesterol, stigmasterol, and 5-avenasterol. All of the above components (Thymoquinone, Linoleic acid, Phytosterols) are known as outstanding compounds with important potential for applications related to human health support. Thymoquinone is our preferred component that makes this dietary supplement special in our view. *The statements in this section have not been evaluated by the FDA or EFSA, but they are under review at EFSA.

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Broccoli Ultra

Broccoli Ultra

Sulforaphane is the compound in broccoli responsible for many of its health benefits. Only a few products available around the world contain the true, free and stabilized sulforaphane that is typically studied by scientists. Nearly all other food supplements contain sulforaphane’s precursor, known as sulforaphane glucosinolate, or glucopharin. For sulforaphane glucosinolate to be absorbed, the human body needs to first convert it into free sulforaphane. For this conversion to take place, a specific enzyme called myrosinase, is required. In nature, both sulforaphane glucosinolate and myrosinase exist inside the broccoli plant. However, food processing, including boiling, degrades most of the myrosinase enzyme found in broccoli and, as a result, very little sulforaphane will finally reach the blood stream. Clinical trials (1) tell us that, without the enzyme myrosinase, only 10% of sulforaphane glucosinolate is converted into free sulforaphane and absorbed by the body. The rest is excreted. This small conversion is facilitated by gut bacteria, and therefore varies from person to person. When sulforaphane glucosinolate and myrosinase are delivered at the same time, a significantly higher conversion of sulforaphane glucosinolate is achieved. Clinical trials estimate the conversion to be approximately 40%, again with variations from person to person (1). It can therefore be deduced that only part of ingested sulforaphane glucosinolate can be converted into the free sulforaphane known for its many health benefits. Furthermore, It is important to note that sulforaphane glucosinolate has a higher molecular weight than free sulforaphane. Thus, 2.5 mg of sulforaphane glucosinolate will generate only 1 mg of free sulforaphane. This becomes significant when we need to estimate how much sulforaphane glucosinolate within a capsule will become free sulforaphane actually available to the body. When making this estimate, we need to consider two aspects: How much sulforaphane glucosinolate is converted into sulforaphane (40% with myrosinase and 10% without myrosinase enzyme). How much of this converted sulforaphane glucosinolate will end up as free sulforaphane from a weight aspect (2.5 mg sulforaphane glucosinolate becomes 1 mg free sulforaphane). Thus, if a capsule contains 100 mg sulforaphane glucosinolate and there is no myrosinase, according to the results of the aforementioned clinical trials, 90 mg will be excreted without having the chance to get to the blood stream. Only 10 mg will be converted into free sulforaphane. Furthermore, due to the difference in molecular weight,10 mg sulforaphane glucosinolate will become only 4 mg free sulforaphane. In other words, 25 mg sulforaphane glucosinolate generates 1 mg free sulforaphane. At MCS Formulas, each capsule of our Broccoli Ultra contains 15 mg free Sulforaphane. This amounts to 30 mg of free sulforaphane per daily dose of two capsules. (This is the equivalent of approximately 750 mg sulforaphane glucosinolate, as stated on the product label.) According to studies performed by others (2), the amount of sulforaphane in a daily dose of MCS Formulas Broccoli Ultra capsules, positions us at the top of the industry. References Sulforaphane Glucosinolate to Sulforaphane conversions in humans with or without Myrosinase: https://pubmed.ncbi.nlm.nih.gov/31261930/ Sulforaphane Glucosinolate to Sulforaphane conversions in the laboratory, with or without Myrosinase: https://www.broq.life/compare https://pubmed.ncbi.nlm.nih.gov/25431127 https://pubmed.ncbi.nlm.nih.gov/31261930/

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Citrus Bergamot

Citrus Bergamot

Citrus bergamot, a distinctive citrus fruit, is the cornerstone of this supplement. Grown in Italy, the fruit offers a unique botanical profile. To ensure consistent quality and potency, this supplement is standardized to contain specific bioactive compounds. Melitidin and Bruteridin, key constituents of bergamot, are present in precise amounts. This standardization process differentiates the product, setting it apart from other bergamot supplements. By focusing on these specific compounds, the supplement delivers a targeted approach. The formulation encapsulates the essence of bergamot while maintaining consistent levels of its active components. This standardized approach allows for precise incorporation into daily routines, providing a reliable dietary addition.

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Citrus Pectin MCP Powder

Citrus Pectin MCP Powder

Pectin, a natural polysaccharide found in the cell walls of most higher plants such as citrus fruits, has gained increasing attention over the past decade due to its relation to Galectin-3, a type of protein involved in many cellular functions. Galectin-3 contains a carbohydrate recognition domain that allows it to bind to sugars found on the surface of cells and extracellular matrix components. Galectin-3 is involved in several cellular activities, including the epithelial–mesenchymal transition (EMT). As a soluble fiber, pectin can absorb water and form a gel-like substance in the digestive tract, providing nourishment for beneficial gut bacteria. Thus, incorporating pectin-rich foods such as apples, citrus fruits, and berries into the diet can be beneficial. The Bioavailability Challenge of Pectin and the Emergence of Modified Citrus Pectin Due to its large molecular size, pectin is poorly absorbed in the small intestine and passes largely intact into the colon. Therefore, in this case, its benefits will be limited mainly to digestive health. To enable pectin to be absorbed into the bloodstream, to increase the chance it can interact with the desired targets, the large pectin molecule has to be broken down into smaller pieces through enzymatic alterations. These smaller pieces of pectin are known as Modified Citrus Pectin (MCP). Therefore, Modified Citrus Pectin is a form of pectin but with a lower molecular weight. MCP has a lower molecular weight than regular pectin, typically less than 20,000 Daltons, compared to pectin’s range of 60,000 to 130,000 Daltons. Modified Citrus Pectin at MCS Formulas: Introducing a New Standard Not all MCP powders are created equal, and most MCP powders available as food supplements are not fully water-soluble. Our new MCS Modified Citrus Pectin formulation stands out for its purity, solubility, and bioavailability. Unlike established MCP powders, ours is highly soluble in water, at room temperature, leading to better bioavailability. This enhanced dissolution increases the potential for effectiveness. *The statements in this section have not been evaluated by the FDA or EFSA.

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Citrus Pectin MCP Pure

Citrus Pectin MCP Pure

Pectin, a natural polysaccharide found in the cell walls of most higher plants such as citrus fruits, has gained increasing attention over the past decade due to its relation to Galectin-3, a type of protein involved in many cellular functions. Galectin-3 contains a carbohydrate recognition domain that allows it to bind to sugars found on the surface of cells and extracellular matrix components. Galectin-3 is involved in several cellular activities, including the epithelial–mesenchymal transition (EMT). As a soluble fiber, pectin can absorb water and form a gel-like substance in the digestive tract, providing nourishment for beneficial gut bacteria. Thus, incorporating pectin-rich foods such as apples, citrus fruits, and berries into the diet can be beneficial. The Bioavailability Challenge of Pectin and the Emergence of Modified Citrus Pectin Due to its large molecular size, pectin is poorly absorbed in the small intestine and passes largely intact into the colon. Therefore, in this case, its benefits will be limited mainly to digestive health. To enable pectin to be absorbed into the bloodstream, to increase the chance it can interact with the desired targets, the large pectin molecule has to be broken down into smaller pieces through enzymatic alterations. These smaller pieces of pectin are known as Modified Citrus Pectin (MCP). Therefore, Modified Citrus Pectin is a form of pectin but with a lower molecular weight. MCP has a lower molecular weight than regular pectin, typically less than 20,000 Daltons, compared to pectin’s range of 60,000 to 130,000 Daltons. Modified Citrus Pectin at MCS Formulas: Introducing a New Standard Not all MCP powders are created equal, and most MCP powders available as food supplements are not fully water-soluble. Our new MCS Modified Citrus Pectin formulation stands out for its purity, solubility, and bioavailability. Unlike established MCP powders, ours is highly soluble in water, at room temperature, leading to better bioavailability. This enhanced dissolution increases the potential for effectiveness. *The statements in this section have not been evaluated by the FDA or EFSA.

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Coriolus Turkey Tail

Coriolus Turkey Tail

Coriolus versicolor, a type of mushroom, has been utilized in traditional medicine for centuries. This fungal source has garnered scientific interest due to its unique composition. Among its constituents are compounds that have been the focus of research. T cells, a key component of the immune system, play a vital role in bodily functions. The relationship between certain compounds found in Coriolus versicolor and T cell activity has been an area of scientific exploration. This supplement harnesses the potential of Coriolus versicolor, offering a natural source of compounds for dietary supplementation. By incorporating this mushroom-derived product into one’s routine, individuals can benefit from its traditional use while contributing to ongoing scientific inquiry.

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Curcumin C Comex

Curcumin C Comex

Curcumin is an active component of Turmeric (Curcuma longa), widely used for medical treatments of various diseases for more than 2500 years in Asian countries. During this long journey Turmeric has become a cornerstone in Ayurveda and traditional Chinese medicine. Research from academic space has indicated that Curcumin is important for multiple aspects related to the human health. This is why multiple clinical studies have been started to evaluate the effectiveness of Curcumin in various human diseases, and some have already started to deliver promising results. In line with the recent findings, it is now believed that Curcumin may add value on the following lines: Helps maintain the health of the liver [EFSA ID 3908]; Helps to control inflammatory responses within the body [EFSA ID 2030]; Helps to promote appetite in cases of loss of appetite [EFSA ID 2744] Prevents the accumulation of fats [EFSA ID 2751] Helps to keep the skin healthy [EFSA ID 4008] Helps to maintain the efficacy of the immune system [EFSA ID 4009] Helps to maintain resistance to allergies [EFSA ID 4009] Supports production and quality of blood [EFSA ID 4010] Supports heart function [EFSA ID 4010] Supports blood circulation [EFSA ID 4010] Helps maintain the health of the lungs and upper respiratory tract [EFSA ID 4011] Supports the function of the nervous system [EFSA ID 4014] *The statements in this section have not been evaluated by the FDA or EFSA, but they are under review at EFSA. The potential added value of Curcumin to the human health is indeed indicated by the fast-growing interest of the academic research. Indeed, a search in PubMed (the largest database of life sciences publications) indicates a total of about 24.000 scientific publications so far. And this may only be the beginning. The academic attention is fast-growing, from only 100 publications in year 2000, to about 2400 publications in year 2023. Therefore, Curcumin has become one of the most outstanding and fascinating plant extract, known to us.

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Danshen

Danshen

Danshen is the dried root of Salvia miltiorrhiza, also called Chinese sage. It contains hydrophilic (salvianolic acid A and B, danshensu, etc.) and lipophilic (dihydrotanshinone, tanshinone I, tanshinone IIa and IIb, etc.) components, intensively researched for their potential added value to human health. Indeed, in Traditional Chinese Medicine, Danshen is a key ingredient used in herbal mixtures to support with various health challnges. Danshen, derived from the root of Salvia miltiorrhiza, is a traditional herbal remedy long used in Chinese medicine. It is celebrated for its potential cardiovascular benefits, including support for healthy blood circulation and heart function. The active compounds in Danshen are believed to promote improved blood flow, provide antioxidant protection, and exert anti-inflammatory effects, all of which contribute to overall circulatory health. Many users incorporate Danshen into their wellness routines to help maintain balanced blood pressure and support heart vitality.

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EGCG

EGCG

EGCG (Epigallocatechin Gallate) is a catechin, a type of plant-based compound found in various plant sources, particularly green tea. As the most abundant catechin in green tea, EGCG contributes significantly to the beverage’s unique properties. EGCG is a flavonoid, a group of compounds known for their antioxidant properties. It possesses a specific molecular structure that contributes to its biological activities. Beyond green tea, EGCG can also be found in other plant-based sources, though in lower concentrations. EGCG has been the subject of scientific research due to its properties and potential applications. Its activity and role in various biological processes have been areas of focus. As research continues to advance, a deeper understanding of EGCG’s characteristics and potential benefits is emerging.

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Gistein Ultra

Gistein Ultra

Genistein is a naturally occurring compound classified as a phytoestrogen, a type of plant-derived compound that exhibits estrogen-like activity. It belongs to the isoflavones family, most commonly found in soybeans and other legumes. For decades, Genistein has been studied for its biochemical properties and how it interacts with various biological systems. Sources of Genistein Genistein is predominantly sourced from soy and Sophora Japonica (Japanese pagoda tree). Soybeans, soy-based foods, and some legumes are the most common dietary sources of Genistein. In addition to dietary sources, genistein supplements have become widely available, especially for individuals who may not consume soy regularly. Genistein’s Biological Activity & How Genistein Works Genistein is particularly investigated in the laboratory for its potential to interact with estrogen receptors. Furthermore, one of the major reasons Genistein has garnered scientific interest is its interaction with tyrosine kinases—enzymes that are vital in cell signaling pathways. Genistein has been shown in lab settings to inhibit the activity of certain tyrosine kinases, which are involved in cell development. This has implications for how cells divide and function. For example, this mechanism has sparked research into Genistein’s potential applications in cellular health and its effects on normal cell function. Forms of Genistein Genistein supplements are available in various forms, including Genistein powder, capsules, and blends like Genistein soy complex. While many supplements are soy-based, some products derive Genistein from Sophora Japonica, offering a soy-free alternative for individuals who have soy allergies or prefer to avoid soy in their diet. Safety While Genistein is a compound found in foods and researched for a long time, some individuals may wonder, “Is Genistein safe?”. Research indicates that when taken at standard dosages, Genistein supplements are generally safe for most people. However, like many compounds, very high doses may lead to side effects. Common Genistein side effects may include mild gastrointestinal discomfort, especially when the supplement is first introduced into the diet. Therefore, it is always advised that Genistein, like other food supplements, it is introduced gradually in the diet. Research and Ongoing Studies Genistein continues to be the subject of scientific investigation, with a particular focus on its role in cell function, and its interactions with hormonal pathways. Research involving Genistein isoflavones often centers on their potential to influence a variety of biological processes. Studies on Genistein’s absorption have also looked into the benefits of combining it with natural compounds such as polysaccharides to improve bioavailability. Conclusion Genistein is a well-researched isoflavone with intriguing properties, especially regarding its interaction with cellular pathways and estrogen receptors. Available through diet or as a supplement, it offers a soy-free option for those interested in supplementing this bioactive compound. As always, it’s important to consult with healthcare professionals before adding any supplement to your regimen, especially to ensure the correct Genistein dosage and monitor for any side effects.

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Glutamine Inhibifour

Glutamine Inhibifour

Glutamine Inhibifour is the first food supplement designed with the GLUTAMINOLYISIS pathway in mind. We have intensively researched the scientific literature and concluded that the following four compounds, typically naturally occurring in various plants, and available as food supplements, stand out when it comes to their connection to the GLUTAMINOLYISIS pathway activity*. URSOLIC ACID – typically found in Rosmarinus Officinalis Leaves, connected to the levels of Glutamine Transporter (ASCT2) (1) 50 mg CAFFEIC ACID – typically found in various foods and Propolis, connected to the levels of Glutaminase (GLS) (2) – note: Caffeic Acid is not related to Caffeine 50 mg HESPERIDIN – typically found in the Bitter Orange, connected to the levels of aminotransferase and aspartate aminotransferase (3) 50 mg EGCG – typically found in Green Tea, connected to the levels of Glutamate dehydrogenase (GDH) (4) Due to their outstanding properties, each of the above compounds have been intensively investigated and addressed in the scientific literature. *The statements in this section have not been evaluated by the FDA or EFSA. References Ursolic acid and ASCT2 https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5705091/ Caffeic Acid and GLS https://pubmed.ncbi.nlm.nih.gov/29958416/ Hesperidin and ALT/AST https://pubmed.ncbi.nlm.nih.gov/28385612/ EGCG and GDH https://pubmed.ncbi.nlm.nih.gov/21813650/

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Glycolysis Inhibithree Phlorizin Shikonin Tanshinone

Glycolysis Inhibithree Phlorizin Shikonin Tanshinone

Glycolysis Inhibithree is a blend of three naturally occurring compounds derived from traditional botanical sources: Phlorizin, Tanshinone IIA, and Shikonin. These compounds are sourced from the bark of apple trees, the roots of Salvia miltiorrhiza (Danshen), and Lithospermum erythrorhizon, respectively. Historically used in traditional practices, these ingredients have been the subject of scientific studies focused on their molecular properties and interactions with cellular systems. Phlorizin – 100 mg Phlorizin Phlorizin is a polyphenolic compound found primarily in the bark of apple trees (Malus domestica). It has been a point of interest in botanical research due to its potential molecular interactions. Scientific studies have explored its interactions with glucose transport systems in various biological contexts, particularly its association with sodium-glucose co-transporters (SGLT1 and SGLT2) (Ref.). These transporters are involved in glucose movement across cell membranes, and research continues to investigate how compounds like Phlorizin interact with these biological systems. Scientific research on Phlorizin primarily focuses on its intracellular mechanism centered on SGLT1 and SGLT2. (Ref.) Tanshinone IIA – 10 mg Tanshinone IIA Tanshinone IIA is extracted from the root of Salvia miltiorrhiza (Danshen), a traditional herb that has been studied for its chemical composition. Among its properties, Tanshinone IIA has been investigated for its connection with HK2 (Hexokinase II) and Lactate Dehydrogenase (LDH) (Ref.), an enzyme involved in metabolic processes such as the conversion of pyruvate to lactate. This connection is of interest to researchers studying energy production and cellular metabolism. Scientific research on Tanshinone IIA primarily focuses on its intracellular mechanism centered on HK2 (Hexokinase II), LDH; NF-κB Pathway and TNF-α, IL-6, and IL-1β; STAT3; mTOR Pathway, nitric oxide (NO), VEGF/VEGFR2; Ferroptosis (Ref.). Shikonin – 8 mg Shikonin Shikonin is a naturally occurring compound derived from the roots of Lithospermum erythrorhizon (Zi Cao). It has been traditionally used in various applications and has attracted attention in modern research due to its unique chemical structure. Studies have explored Shikonin’s association with Pyruvate Kinase M2 (PKM2), a key enzyme involved in glycolytic pathways (Ref.). This research is ongoing, particularly in understanding how compounds like Shikonin interact with metabolic enzymes. Scientific research on Shikonin primarily focuses on its intracellular mechanism centered on Pyruvate Kinase M2 (PKM2) as well as NF-κB, PI3K/Akt/MAPKs, Akt/mTOR, TGF-β, GSK3β, TLR4/Akt. As such, Glycolysis Inhibithree is a unique food supplement designed with the GLYCOLYSIS (Fermentation) pathway in mind. Each of the ingredients in Glycolysis Inhibithree is sourced from natural plant-based materials with a long history of traditional use. Modern scientific studies have focused on their molecular interactions with enzymes and transporters within biological systems, especially related to sodium-glucose co-transporters, HK2 (Hexokinase II) and Pyruvate Kinase M2 (PKM2). While Glycolysis Inhibithree does not make any claims about health benefits, the ingredients have been extensively researched in the context of their interactions with cellular and biochemical processes. *The statements in this section have not been evaluated by the FDA or EFSA.

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Grape Seed Extract

Grape Seed Extract

Grape seed extract is derived from the seeds of grapes. Its primary active components are Oligomeric Proanthocyanidins (OPCs), a class of compounds found in various plant sources. OPCs are naturally produced by plants as a defense mechanism. Unlike many plant extracts, OPCs demonstrate good bioavailability, allowing for potential absorption within the body. The relationship between OPCs and the human body is a subject of ongoing scientific research. These compounds have been studied in various contexts, including cardiovascular health, skin, immunity, brain function, digestive processes, and metabolic factors. The interplay between OPCs and the gut microbiome, such as Bifidobacterium spp. and Lactobacillus spp., is an emerging area of interest in the scientific community. Intracellular mechanisms researched in relation to OPC: EMT, TGF- β Signaling Pathway, MMP-2 and MMP-9, VEGF and angiopoietin 1, HIF-1α-dependent pathway, NF-κB signaling, TNF-α, IL-6, and COX-2. *The statements in this section have not been evaluated by the FDA or EFSA.

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GrePropolis

GrePropolis

Propolis is a honeybee product with a resinous texture, it’s made from the bark and sprouts of several plants by bees. They make propolis, often referred to as “bee glue,” for several essential purposes within the hive. Here are some of the primary reasons why bees produce and use propolis: Sealing and Reinforcing the Hive: Bees use propolis to seal gaps and crevices in the hive. This serves as a protective barrier against drafts, rain, and other external elements. By closing openings in the hive structure, bees maintain a stable and controlled environment for the colony. Sterilization and Hygiene: Propolis possesses natural antimicrobial and antifungal properties useful in the hive. As a result, bees use it to coat the interior surfaces of the hive, including the walls and the entrance. This action creates a more hygienic environment by preventing the growth of bacteria and fungi, thus contributing to the overall health of the colony. Defense Against Predators: The sticky and resinous nature of propolis makes it an effective deterrent against invaders, such as ants or other small predators. Bees may use propolis to narrow hive entrances or create obstacles that impede the progress of unwanted visitors. Preserving Hive Cleanliness: Bees are meticulous about maintaining a clean and sterile environment within the hive. They use propolis to encapsulate foreign objects or debris that might find their way into the hive. This encapsulation prevents the intrusion of potential contaminants. Preventing Diseases: Propolis has been observed to have medicinal properties that can help bees. As such, bees use it as a defense mechanism against pathogens, helping to prevent the spread of diseases within the hive. In summary, bees make propolis as a versatile and adaptive substance that serves multiple functions, ranging from hive maintenance and protection to contributing to the overall health and well-being of the colony. The composition and sources of propolis can vary, with different plant resins contributing to its unique properties in different regions of the world. Of all propolis types, The New Zealand propolis and the Brazilian Green propolis are the two main kinds that have been extensively studied in recent years, due to their outstanding potential related to human health. Green propolis is a propolis variety that is made from the Baccharis dracunculifolia, a plant species native to Brazil. Bees modify the harvested resin with their enzymes, resulting in the creation of green propolis with distinct chemical compositions and beneficial properties. The particular components typically present in Organic green propolis include: Those derived from cinnamic acid (namely, artepillin, baccarin, p-coumaric acid and drupanin) Flavonoids such as caffeic acid or kaempferol Artepillin C, is a compound that is unuique to Green Propolis, and it has been shown to modulate p21-activated kinase (PAK1) activation. PAK1 on the other hand, has been reported to be connected to NF-κB, making Artepillin C an interesting candidate for additional studies.* *The statements in this section have not been evaluated by the FDA or EFSA.

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HCA Garcinia

HCA Garcinia

Hydroxycitric Acid (HCA) is a derivative of citric acid. It comes from the fruit Garcinia Cambogia that grows in the rainforests of Southeast Asia and South America. Garcinia has been used for centuries in Asian countries for culinary purposes in place of lemon. It has a characteristic sweet and sour taste. Aside from its use as a condiment in cuisine, Garcinia has been used in the traditional Ayurvedic medicine to address various health challenges. One of the main mechanism behind its use in the traditional medicine is believed to be related to its capability to inhibit ATP citrate lyase (ACLY), an enzyme that represents an important step in fatty acids and cholesterol biosynthesis inside cells (EFSA ID 2057, 2643, 2651).

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Hydroxy Tyrosol

Hydroxy Tyrosol

Hydroxytyrosol (HXT) is a phenolic compound extracted from the olive and olive leaves. Hydroxytyrosol is generated by the conversion of oleuropein, another important substance present in olives. The conversion occurs during olive ripening or when the olive tissue is damaged by pathogens, herbivores, or mechanical damage, where it acts as an antimicrobial to protect the plant (1). The highest concentration of HXT is found in olive leaves. However, it is lost during oil manufacturing. HXT has been extensively investigated during the last twenty years due to its outstanding potential for human health support. Relevant areas investigated in the scientific literature are related to the impact of HXT on e.g. the cell wall of Candida albicans (2). In oncology field, the impact of HTX on mechanisms such as thioredoxin system, cancer stem cells, pithelial-to-mesenchymal transition, Wnt/β-catenin and TGFβ signaling pathways (3), as well as on myeloid-derived suppressor cells (MDSCs) (4) has been studied intensively. *The statements in this section have not been evaluated by the FDA or EFSA, but they are under review at EFSA. Science & Research Do you want to learn more about the science behind Hydroxytyrosol and the related cellular mechanisms? Please go to our Health & Science section that will be soon expanded to cover many important scientific findings. References https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874578/ https://pubmed.ncbi.nlm.nih.gov/23721186/ https://pubmed.ncbi.nlm.nih.gov/30460610/ https://pubmed.ncbi.nlm.nih.gov/34858184/

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Long Pepper

Long Pepper

Long Pepper (also called Piper Longum, Pippali), is a plant with South Asian origin, cultivated for its fruits used as a spices and seasoning of dishes. It is one of the most important ingredients in Ayurvedic medicine, where it is used for a wide type of health challenges. During the past decades, scientist have discovered Piperlongumine (also called Piplartine) as one of the most relevant and major alkaloid constituent of the fruit of the Long Pepper, responsible for many of Long Pepper’s positive properties. Inline with its traditional use and scientific findings, Long Pepper is believed to contribute in the following area: Long Pepper has adaptogenic properties [ID 2117]; (adaptogenesis is measurable in several ways, e.g. effect of endocrine hormone AND homeostasis.) * Supports the body’s resistance to stress. Helps the body to deal with stress [ID 2117] * Strengthens the immune system [ID 2118] * Supports lung function as Decongestant [ID 2119] * Supports digestion [ID 2120] * Supports the absorption and utilization of other herbal ingredients [ID 2120] * Beneficially affects the heart and cardiovascular system [ID 2478] * Other widely-used adaptogen plants include e.g. Ashwagandha.

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Lycope Us

Lycope Us

Lycopene, a vibrant red carotenoid pigment, is a naturally occurring compound found in certain fruits and vegetables. Notably prevalent in tomatoes, watermelons, pink grapefruits, papayas, and apricots, lycopene contributes to their characteristic hue. Discovered in 1876 within tomato plants, this compound has since become a subject of extensive scientific exploration. As a member of the carotenoid family, lycopene shares structural similarities with other pigments such as beta-carotene. However, its unique molecular configuration imparts distinct properties. Over the decades, research into lycopene has expanded significantly, with thousands of studies dedicated to understanding its characteristics and potential roles in various biological systems. Lycopene has also been studies in relation to the mevalonate pathway. Given the widespread interest in lycopene, many people consider it beneficial to include foods rich in this compound in their diet. Lycopene is found in good amounts in specific vegetables and fruits. Additionally, some choose to enhance their intake by using food supplements that contain lycopene. Lycopene is typically difficult to absorb due to its poor water solubility. It has been suggested that ingesting lycopene together with oil may help increase its bioavailability. However, our Lycopene is embedded in a corn starch matrix, enhancing its water solubility.

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Magnesium Gluconate

Magnesium Gluconate

Magnesium is one of the most vital minerals for the human body and brain, playing a key role in numerous essential functions. Its benefits include: Supporting the normal functioning of the nervous system Contributing to healthy muscle function Aiding in protein synthesis within the body Enhancing brain functions related to learning ability Helping maintain strong bones While magnesium is commonly found in many foods and can be absorbed through a balanced diet, ensuring adequate intake of the recommended 350 mg of elemental magnesium daily is important. To achieve this, magnesium supplements are often a helpful option. However, with various forms of magnesium supplements available – such as sulfate, lactate, hydroxide, oxide, chloride, and gluconate -choosing the right one can be challenging. At MCS Formulas, we’ve carefully selected Magnesium Gluconate as one of the most effective forms of magnesium supplementation. According to the literature, Magnesium Gluconate may be better absorbed and may cause less digestive discomfort, such as diarrhea (2). Additionally, recent studies suggest that gluconate supports cellular absorption of citrate (3), adding further value to this form. For these reasons, we believe Magnesium Gluconate is the optimal choice for magnesium supplementation. References Magnesium Average Daily Intake https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2015.4186 Magnesium Gluconate is one of the Best Options https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855626/ and https://pubmed.ncbi.nlm.nih.gov/7977315/ Gluconate and Citrate Absorption https://cancerres.aacrjournals.org/content/canres/78/10/2513.full.pdf

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Maitake Extract Pure Ml

Maitake Extract Pure Ml

Maitake, a distinctive mushroom species scientifically known as Grifola frondosa, has a rich history rooted in traditional practices. It is one of the most promising medicinal mushrooms, next to mushrooms such as Cordyceps, Reishi, Turkey Tails and Agaricus. Native to East Asia, this mushroom has been cultivated for centuries. Its name means “dancing mushroom” in Japanese, as it caused the delighted discoverers in ancient times to have a dance of joy. Characterized by its unique, fan-like clusters, Maitake has garnered attention in recent times. The mushroom’s composition includes a variety of compounds (including beta-glucans, niacin, pantothenic acid, and lectin), among which beta-glucans have been a subject of scientific interest. These compounds are naturally occurring substances found in the cell walls of many fungi. Cultivating Maitake mushrooms requires specific environmental conditions to ensure optimal growth and compound concentration. The process involves careful attention to factors such as temperature, humidity, and substrate composition. Once harvested, the mushrooms undergo processing to extract valuable components. This supplement leverages advanced extraction techniques to capture the essence of the Maitake mushroom. By concentrating key constituents, the supplement provides a convenient and standardized way to incorporate Maitake into one’s diet. This approach allows for consistent consumption of the mushroom’s natural compounds.

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Mega Flax Seed Lignans

Mega Flax Seed Lignans

Flaxseed, derived from the flax plant (Linum usitatissimum), has been cultivated for centuries. Flaxseed is renowned for its rich content of lignans, particularly secoisolariciresinol diglucoside (SDG). SDG is a type of phytoestrogen, a naturally occurring plant compound. Our flaxseed supplement is specially formulated to deliver a concentrated source of SDG, providing you with a unique component found in flaxseed. In addition to lignans, flaxseed is also an excellent source of dietary fiber, protein, and essential fatty acids, including omega-3 fatty acids. These nutrients contribute to the versatile nature of flaxseed, making it a valuable addition to various dietary practices. Our flaxseed supplement is designed to be easy to incorporate into your daily routine, whether you’re blending it into smoothies, stirring it into yogurt, or simply taking it as a capsule. The presence of SDG in our flaxseed supplement highlights the remarkable nature of this tiny seed. As a phytoestrogen, SDG is one of the many fascinating compounds that have been extensively studied for their unique properties. While flaxseed’s contributions to wellness have been celebrated throughout history, modern research continues to explore and expand our understanding of this remarkable seed. Our flaxseed is carefully selected and processed to maintain its natural integrity, ensuring that you receive a product of the highest quality. Each batch undergoes rigorous testing to ensure purity and potency, so you can trust that you are getting the best that nature has to offer. We are committed to providing a product that you can rely on, backed by our dedication to excellence and transparency.

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Milk Thistle Silymarin

Milk Thistle Silymarin

Milk thistle, scientifically known as Silybum marianum, is a plant native to the Mediterranean region. Its distinctive leaves are often spotted with white, resembling milk. The seeds of milk thistle are the primary source of interest due to their nutritional content. Milk thistle seeds contain a complex mixture of compounds, including silymarin, a flavonoid complex. Silymarin is the primary bioactive component of milk thistle and has been the subject of intensive scientific research (more than 4700 scientific articles have been published on silymarin and its potential added value to life, as indicated at the National Library of Medicine on PubMed). Silymarin is composed of several individual flavonoids, including silybin, silydianin, and silychristin. As a natural compound, silymarin has been incorporated into various dietary supplements and traditional remedies. One of the main reason for Silymarin to be used in supplements and traditional remedies is related to the possibility that it may add value on the following lines: may support the liver health & liver protection [EFSA ID 3821 and 4141]* may contribute to the detoxifying potential of the liver / maintenance of the liver function and additionally promotion of the digestion and the body’s purification [EFSA ID 3821 and 4141]

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N-Acetyl-L Cysteine

N-Acetyl-L Cysteine

N-Acetyl Cysteine (NAC) is a sulfur-containing amino acid derivative. As a naturally occurring compound, it plays a role in various biological processes. Derived from the amino acid cysteine, NAC has garnered attention for its potential applications. In its supplement form, NAC offers a concentrated source of this compound. This molecule is characterized by its unique chemical structure, which contributes to its properties. NAC is involved in several biochemical pathways and serves as a precursor for the synthesis of glutathione, an antioxidant. NAC has been the subject of scientific research exploring its properties and potential applications. Studies have investigated its role in various biological systems, including its antioxidant capacity and involvement in cellular processes.

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Nattokinase FU

Nattokinase FU

Nattokinase is a potent enzyme derived from natto, a traditional Japanese fermented soybean dish. Natto, a fermented cheese-like food, has been a staple in Japanese cuisine for over thousands of years. It consists of soybeans that are cooked and fermented with the action of the bacterium Bacillus subtilis. It is celebrated for its potential to support cardiovascular health by helping to break down fibrin, a protein involved in blood clot formation. By promoting healthy blood flow and vessel flexibility, nattokinase may contribute to reducing the risk of clot-related issues and supporting overall heart function. Additionally, some research suggests it can help maintain healthy blood pressure and improve circulation, making it a popular choice for those looking to naturally support their cardiovascular system.

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Omega Pure

Omega Pure

The food we consume can significantly impact our physical functions and metabolism, especially when it comes to essential substances that the body cannot produce on its own. Omega-3 fatty acids are a prime example of such vital nutrients. They are key components of lipid metabolism and play an important role in human physiology. The omega-3 fatty acids most relevant to human health include alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). However, humans cannot naturally produce Omega-3 fatty acids, making a diet rich in these nutrients essential. Specifically, the body can only obtain EPA and DHA through dietary intake, or in limited amounts, by converting ALA from food. As we age, the body’s ability to convert ALA into essential Omega-3s like DHA may decline. Fatty fish, which are naturally rich in EPA and DHA, are a key part of official dietary guidelines for a balanced diet. However, many people do not consume enough fatty fish to meet the recommended daily intake of these essential omega-3s. There are various reasons for this shortfall, but fish remains our primary source of EPA and DHA. At the same time, official recommendations suggest limiting fish consumption due to potential contamination from environmental pollutants such as dioxins, PCBs, and heavy metals like mercury. These concerns do not extend to high-quality fish oil supplements, which are purified to minimize or eliminate these contaminants. As a result, many individuals now opt for daily fish oil supplements as a reliable way to ensure they get the full benefits of these important polyunsaturated long-chain fatty acids. When it comes to Omega-3 fatty acid status, that refers to the levels of EPA and DHA in the body, which can now be measured through tests such as a finger-prick blood test. This test determines the omega-3 index, which reflects the percentage of EPA and DHA in the cell membranes of red blood cells, offering a reliable measure of omega-3 levels. The omega-3 index is closely linked to the amount of long-chain omega-3 fatty acids in various tissues and organs, including the heart. Current research suggests that an optimal omega-3 index is at least 8%. Achieving this level may require higher doses of EPA and DHA, particularly for individuals following a typical Western diet, which is often high in omega-6 fatty acids. For those with a lower omega-3 index (around 4.5%, which is common in Western populations), supplementing with 2 grams of EPA/DHA daily can help raise the index to around 8% within about three months. For ongoing maintenance, a daily intake of 700-1000 mg of EPA/DHA may be sufficient, depending on dietary habits. Permitted health claims: DHA contributes to maintenance of normal brain function DHA contributes to the maintenance of normal vision DHA contributes to the maintenance of normal blood triglyceride levels DHA and EPA contribute to the maintenance of normal blood pressure DHA and EPA contribute to the maintenance of normal blood triglyceride levels EPA and DHA contribute to the normal function of the heart References Omega 3 fatty acids such as DHA from ALA in aging https://www.plefa.com/article/S0952‐3278(06)00090‐1/fulltext EFSA evaluation on EPA and DHA and its beneficial effect on cardiovascular system http://www.efsa.europa.eu/en/efsajournal/doc/1796.pdf Recent Clinical Trials Shed New Light on the Cardiovascular Benefits of Omega‐3 Fatty Acids https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6822654/

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Pure Berberine

Pure Berberine

Berberine is a dietary supplement, the principal bioactive ingredient various plants such as Berberis vulgaris (barberry) and Berberis Aristata and in common traditional Chinese medicinal herbs (also named ‘Huang Lian’ in Chinese) traditionally used to address various health challenges. It comes from the roots, stems, and bark of various plants. According to inscriptions found on clay tablets in the library of the Assyrian Emperor Ashurbanipal, one of the earliest use of Berberine containing fruits goes back to 650 BCE. These tablets refer to the purifying effects of Berberine-containing fruits. In Ayurvedic medicine, Berberine was used for example for ‘open the mind’. The plant use in Chinese medicine dates back over 3000 years, and it’s use in the European countries has a similarly long history. Today, Berberine is widely used in Asian countries (mainly in China) due to its good clinical and safety profile. In US, FDA considers Berberine safe for human use. In line with the traditional use, and the recent findings, currently Berberine is considered: Good for liver* [EFSA ID 3989] Good for blood glucose* [EFSA ID 4363] Good for cholesterol* [EFSA ID 3272]

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Pure Honokiol

Pure Honokiol

Honokiol is a less known food supplement but with wonderful potential. It is a natural extract from Magnolia bark, used for centuries in traditional medicine in China, Korea, and Japan, due to its perfect combination of bioavailability and ability to support the body through a wide range of mechanisms, often reflected in the scientific research performed on Honokiol, during the past decades.

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Quercetin Bromelain

Quercetin Bromelain

Quercetin and Bromelain are a dynamic duo in the world of natural compounds, each with its own fascinating origin and history. Quercetin, a naturally occurring flavonoid, is found in a wide variety of fruits, vegetables, and grains. Historically, it has been appreciated for its role in giving these foods their vibrant colors and has been a subject of scientific curiosity for decades due to its diverse properties. From apples and onions to tea and berries, quercetin has been consumed by humans for centuries, with modern research continuing to explore its potential. Bromelain, on the other hand, originates from the stem and fruit of pineapples, native to South America. First isolated in the late 19th century, bromelain has been prized for its proteolytic enzyme activity, making it a popular natural extract. Traditionally used in tropical regions, it became well-known outside of these areas for its wide range of applications, from culinary uses to scientific investigations. Together, quercetin and bromelain create a powerful supplement combination, harmonizing the rich, natural benefits of plant-based compounds. Quercetin brings its bioflavonoid properties, while bromelain enhances absorption and brings its own unique enzymatic abilities. This fusion, derived from plants with deep cultural and scientific roots, has led to an exciting partnership in the natural supplement world, offering new possibilities for daily wellness.

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Reishi Extract Pure Ml

Reishi Extract Pure Ml

Reishi, also known as Ganoderma lucidum, is a legendary mushroom with a rich history that spans thousands of years. Often referred to as the “Mushroom of Immortality” in ancient Chinese medicine, Reishi has been revered in Asian cultures for its remarkable properties and has held a prestigious place in traditional health practices. The origins of Reishi use can be traced back to more than 2,000 years ago, where it was highly prized by emperors and healers for its rare availability and its perceived ability to promote good health, perpetual youth, vitality, and longevity. Described as holy mushroom, it has been thought to be a mushroom growing in the “houses of immortals”. According to Chinese Pharmacopoeia, Reishi acts to restore Qi (the energy of life). In the wild, Reishi mushrooms grow in humid, forested areas on decaying hardwood trees, especially in regions of Asia. Though traditionally consumed in whole form as a tea or powder, modern scientific exploration has led to the refinement of Reishi into potent extracts, which offer more targeted benefits. Typically, Reishi may containing various compounds such as glycoproteins, polysaccharides, triterpenoids, meroterpenoids, sesquiterpenoids, steroids, alkaloids, benzopyran derivatives, and benzoic acid derivatives, and minerals such as potassium, calcium, phosphorus, magnesium, selenium, iron and zinc. Of these, the most important constituents of Reishi for human health are believed to be polysaccharides and triterpenes. Extracts containing high amounts of polysaccharides, in particular, are highly valued for their concentrated bioactive components, providing an advantage over using the whole mushroom. Polysaccharides, especially beta-glucans, are among the most important compounds found in Reishi mushrooms. Beta-glucans are complex carbohydrates that have attracted significant scientific interest due to their potential ability to support immune system function (EFSA ID 3764)*.

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Scutellaria Extract

Scutellaria Extract

Scutellaria baicalensis, commonly known as Baikal Skullcap, is an ancient herb with deep roots in traditional Chinese medicine. Its use dates back over 2,000 years, where it was regarded as one of the “50 Fundamental Herbs” in Chinese herbalism. Indigenous to the shores of Lake Baikal in Siberia and other parts of East Asia, this hardy plant thrives in harsh climates and has been prized for its vibrant purple flowers and potent bioactive compounds. Scutellaria baicalensis has long been cherished for its unique properties, particularly in maintaining balance and promoting wellness. What makes Scutellaria baicalensis particularly special is the presence of a powerful flavonoid called baicalein, which is one of the key bioactive components of this plant. Baicalein, along with other flavones found in the root of the plant, has been extensively studied in modern science for its diverse properties. Baicalein stands out due to its unique molecular structure, which gives it distinct characteristics. Unlike many other plants, Scutellaria baicalensis is especially rich in baicalein, making it a vital species for both traditional and modern herbal practices. The Baicalein compound, primarily found in the root of Scutellaria baicalensis, is recognized for its ability to interact with various biochemical pathways in the body. This has led to an increasing interest in its potential applications within the realm of natural supplementation. Baicalein’s bioactivity has spurred a resurgence in research, as scientists seek to understand how this ancient remedy can contribute to modern health practices. The history of Scutellaria baicalensis is as rich and complex as the compounds it contains. From the herbal compendiums of ancient China to the laboratories of modern researchers, Baikal Skullcap remains a fascinating plant whose properties continue to be explored.

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Super Artemisinin

Super Artemisinin

Artemisinin is a potent antimalarial compound derived from the Artemisia annua plant, which is native to Asia and Africa. This compound has been used for centuries in traditional medicine to treat various ailments, including malaria. This compound has strong antiparasitic properties, and it is believed to be effective against a wide range of parasites, including Plasmodium falciparum, the parasite responsible for malaria.

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Super GreTea Extract

Super GreTea Extract

Green Tea Extract has captivated cultures for centuries, originating from the ancient tea plantations of China and Japan. The story of green tea begins over 4,000 years ago, where it was not only revered as a daily beverage but also regarded for its potential benefits. This long history of use laid the foundation for modern science to explore and confirm the rich, complex compounds found in green tea. Extracts of green tea, particularly standardized versions, offer a concentrated form of its most prized compounds, making them an increasingly popular choice for those looking to tap into its potential. One of the key elements in green tea extract is a polyphenol known as Epigallocatechin Gallate (EGCG), which has garnered significant attention from researchers due to its unique properties. EGCG is one of the most abundant catechins in green tea, standing out as a powerful compound that makes up a significant portion of the plant’s bioactive profile. Green tea leaves are carefully harvested from the Camellia sinensis plant, and the extraction process focuses on isolating these valuable polyphenols, with EGCG taking center stage. The presence of catechins, particularly EGCG, distinguishes green tea from other teas, as the minimal processing of green tea allows these compounds to remain intact. Unlike black or oolong tea, which undergo more oxidation, green tea preserves its natural antioxidant profile, making it a standout in the world of botanicals. Green tea extract supplements offer a convenient way to consume high levels of these polyphenols without needing to drink multiple cups of tea daily. Standardized extracts ensure consistent levels of EGCG and other catechins, providing a more concentrated form of what makes green tea so unique. The inclusion of EGCG in supplements highlights its importance, as it’s this compound that continues to be at the forefront of scientific inquiry, driving the ongoing fascination with green tea’s potential.

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Super Olive Leaf Extract

Super Olive Leaf Extract

Olive leaf (Olea europaea) was first used medicinally in the Ancient Egypt. In the Bible, the olive plant is often mentioned in reference to its medicinal use. Latter, pulverized leaves were used in drinks to support in case of various health challenges. According to the scientific literature, Olive leaves are rich in polyphenolic compounds that have been found to have a large amount of important functions. The main component of Olive leaves associated to such properties is called Oleuropein, that gives olive leafs (and oils) a bitter taste. In line with both its traditional use and scientific research, Olive Leaf Extract it is believed to help in the various areas of health, such as helping regulate blood pressure (EFSA ID 2656)*.

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Ultra TQ Black Cumin

Ultra TQ Black Cumin

Black Cumin Seed and its Oil (also called Nigella sativa) is a natural dietary supplement, that has been used by various civilization around the world for centuries. It has been used both as a spice and flavoring agent in a variety of food preparations, as well as a traditional medicine to address various animal and human ailments. Due to its contribution to life, Black Cumin has a very rich history, and it has been even called ”the seed of blessing”. Black cumin seeds have been found in the tomb of Egyptian Pharaoh Tutankhamen, as one of the several accompanying articles. Hippocrates and Dioscorides spoke about it as ‘Melanthion’, while the Bible describes it as the “curative black cumin” (Isaiah 28:25, 27 NKJV). Based on all its history and recent science, some argue that this is one of the most powerful medicinal plants known to man. Black cumin seeds contain multiple compounds such as very small amounts of Thymoquinone as well as major sterols such as β-sitosterol, campesterol, stigmasterol, and 5-avenasterol. Of these, Thymoquinone, is believed to be the most relevant bioactive constituent of Black Cumin seed, with important potential for applications related to human health support.

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Urolithin A

Urolithin A

Urolithin A is a bioactive metabolite that is not directly found in food but is naturally produced in the body through the transformation of ellagitannins, compounds found in ellagic acid-rich foods such as pomegranates, walnuts, and berries (Ref.). Once consumed, gut microbiota convert ellagitannins into Urolithin A, a process that varies between individuals (Ref.) due to differences in gut microbiome composition (Enterocloster species (Ref.)). Our Urolithin A 500mg daily dose (delivered in two capsules) provides a pure and standardized source of Urolithin A, bypassing the variability of natural conversion and ensuring a consistent and effective intake. Urolithin A has been explored in preclinical and clinical studies investigating its role in cellular metabolism, mitochondrial bioenergetics, and metabolic pathways (Ref). It has been studied in the context of aging-related research, with a growing body of literature examining its interactions with cellular energy production and autophagic processes. Since the body’s natural ability to produce Urolithin A depends on gut microbiome efficiency, supplementation provides a direct and reliable source of this compound, ensuring consistent levels independent of individual microbiota variations.

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Vitamin Bottle D

Vitamin Bottle D

Vitamin D3, also known as cholecalciferol, is a fat-soluble vitamin that plays a crucial role in maintaining overall health. It is naturally produced in the skin upon exposure to sunlight, and can also be obtained from certain foods and supplements. Authorized health claims: Vitamin D is needed for normal growth and development of bone in children Calcium and vitamin D help to reduce the loss of bone mineral in post-menopausal women Vitamin D helps to reduce the risk of falling associated with postural instability and muscle weakness Vitamin D contributes to normal absorption/utilisation of calcium and phosphorus Vitamin D contributes to normal blood calcium levels Vitamin D contributes to the maintenance of normal bones Vitamin D contributes to the maintenance of normal muscle function Vitamin D contributes to the maintenance of normal teeth Vitamin D contributes to the normal function of the immune system Vitamin D has a role in the process of cell division Vitamin D contributes to the normal function of the immune system in children

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